| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM36819 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM36819 |
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| n/a |
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| Name | BDBM36819 |
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| Synonyms: | 3-Amino-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carboxylic acid cyclopentylamide | 3-amino-N-cyclopentyl-6-(2-thienyl)thieno[2,3-b]pyridine-2-carboxamide | 3-amino-N-cyclopentyl-6-thiophen-2-yl-2-thieno[2,3-b]pyridinecarboxamide | 3-amino-N-cyclopentyl-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide | 3-azanyl-N-cyclopentyl-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carboxamide | MLS000074341 | SMR000014004 | cid_645027 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17N3OS2 |
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| Mol. Mass. | 343.466 |
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| SMILES | Nc1c(sc2nc(ccc12)-c1cccs1)C(=O)NC1CCCC1 |
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| Structure | 
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