| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83466 |
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| n/a |
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| Name | BDBM83466 |
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| Synonyms: | MLS000068342 | N-(3-Cyano-4,5-dimethyl-thiophen-2-yl)-2-(3-tetrazol-1-yl-phenoxy)-acetamide | N-(3-cyano-4,5-dimethyl-2-thienyl)-2-[3-(tetrazol-1-yl)phenoxy]acetamide | N-(3-cyano-4,5-dimethyl-2-thiophenyl)-2-[3-(1-tetrazolyl)phenoxy]acetamide | N-(3-cyano-4,5-dimethyl-thiophen-2-yl)-2-[3-(1,2,3,4-tetrazol-1-yl)phenoxy]ethanamide | N-(3-cyano-4,5-dimethylthiophen-2-yl)-2-[3-(tetrazol-1-yl)phenoxy]acetamide | SMR000002020 | cid_647106 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N6O2S |
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| Mol. Mass. | 354.386 |
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| SMILES | Cc1sc(NC(=O)COc2cccc(c2)-n2cnnn2)c(C#N)c1C |
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| Structure | 
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