| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83477 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83477 |
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| n/a |
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| Name | BDBM83477 |
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| Synonyms: | 2-amino-7-keto-8,10-dimethyl-4-phenyl-4H-furo[1,2]cyclohepta[4,6-d]pyran-3-carbonitrile | 2-amino-8,10-dimethyl-7-oxo-4-phenyl-4H-furo[1,2]cyclohepta[4,6-d]pyran-3-carbonitrile | 2-azanyl-8,10-dimethyl-7-oxidanylidene-4-phenyl-4H-furo[1,2]cyclohepta[4,6-d]pyran-3-carbonitrile | MLS000042791 | SMR000046489 | cid_665296 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16N2O3 |
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| Mol. Mass. | 344.3633 |
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| SMILES | Cc1oc(C)c2c1c1OC(=N)C(C#N)C(c3ccccc3)c1ccc2=O |
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| Structure | 
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