| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | 96100±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83558 |
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| n/a |
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| Name | BDBM83558 |
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| Synonyms: | 1-[4-[(4-chlorobenzyl)amino]-3-nitro-phenyl]-3-methyl-pyrrolidine-2,5-quinone | 1-[4-[(4-chlorophenyl)methylamino]-3-nitro-phenyl]-3-methyl-pyrrolidine-2,5-dione | 1-[4-[(4-chlorophenyl)methylamino]-3-nitrophenyl]-3-methylpyrrolidine-2,5-dione | 1-{4-[(4-chlorobenzyl)amino]-3-nitrophenyl}-3-methylpyrrolidine-2,5-dione | MLS000584616 | SMR000207201 | cid_12005260 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16ClN3O4 |
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| Mol. Mass. | 373.79 |
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| SMILES | Cc1cc(O)n(c1O)-c1ccc(NCc2ccc(Cl)cc2)c(c1)[N+]([O-])=O |
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| Structure | 
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