| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83664 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | 9430±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83664 |
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| n/a |
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| Name | BDBM83664 |
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| Synonyms: | 4-[[(2-keto-1,3,3-trimethyl-indolin-5-yl)sulfonylamino]methyl]-N-[(5-methyl-2-furyl)methyl]benzamide | MLS001124561 | N-[(5-methyl-2-furanyl)methyl]-4-[[(1,3,3-trimethyl-2-oxo-5-indolyl)sulfonylamino]methyl]benzamide | N-[(5-methylfuran-2-yl)methyl]-4-[[(1,3,3-trimethyl-2-oxidanylidene-indol-5-yl)sulfonylamino]methyl]benzamide | N-[(5-methylfuran-2-yl)methyl]-4-[[(1,3,3-trimethyl-2-oxoindol-5-yl)sulfonylamino]methyl]benzamide | SMR000628632 | cid_20903324 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27N3O5S |
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| Mol. Mass. | 481.564 |
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| SMILES | CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)NCc1ccc(cc1)C(=O)NCc1ccc(C)o1 |
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| Structure | 
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