| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83670 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83670 |
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| n/a |
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| Name | BDBM83670 |
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| Synonyms: | 1-[4-[4-(4-methylfuro[3,2-c]quinolin-2-yl)carbonylpiperazin-1-yl]phenyl]ethanone | 1-[4-[4-(4-methylfuro[3,2-c]quinoline-2-carbonyl)piperazin-1-yl]phenyl]ethanone | 1-[4-[4-(4-methylfuro[3,2-c]quinoline-2-carbonyl)piperazino]phenyl]ethanone | 1-[4-[4-[(4-methyl-2-furo[3,2-c]quinolinyl)-oxomethyl]-1-piperazinyl]phenyl]ethanone | MLS000924892 | SMR000623739 | cid_20868577 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H23N3O3 |
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| Mol. Mass. | 413.4684 |
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| SMILES | CC(=O)c1ccc(cc1)N1CCN(CC1)C(=O)c1cc2c(C)nc3ccccc3c2o1 |
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| Structure | 
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