| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
|---|
| Ligand | BDBM49192 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
|---|
| EC50 | 48400±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Endoribonuclease toxin MazF |
|---|
| Name: | Endoribonuclease toxin MazF |
|---|
| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 12100.43 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130689 |
|---|
| Residue: | 111 |
|---|
| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
|---|
| BDBM49192 |
|---|
| n/a |
|---|
| Name | BDBM49192 |
|---|
| Synonyms: | (3-Cyano-7-methoxy-quinolin-2-ylsulfanyl)-acetic acid methyl ester | 2-[(3-cyano-7-methoxy-2-quinolinyl)thio]acetic acid methyl ester | 2-[(3-cyano-7-methoxy-2-quinolyl)thio]acetic acid methyl ester | MLS000070306 | SMR000001741 | cid_656385 | methyl 2-(3-cyano-7-methoxy-quinolin-2-yl)sulfanylethanoate | methyl 2-(3-cyano-7-methoxyquinolin-2-yl)sulfanylacetate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H12N2O3S |
|---|
| Mol. Mass. | 288.322 |
|---|
| SMILES | COC(=O)CSc1nc2cc(OC)ccc2cc1C#N |
|---|
| Structure | 
|
|---|
Search and Browse
