| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83478 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83478 |
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| n/a |
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| Name | BDBM83478 |
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| Synonyms: | MLS000057525 | N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetamide | N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-2-[1,3-dimethyl-2,6-bis(oxidanylidene)purin-7-yl]ethanamide | N-[4-(2-chlorophenyl)-2-thiazolyl]-2-(1,3-dimethyl-2,6-dioxo-7-purinyl)acetamide | N-[4-(2-chlorophenyl)thiazol-2-yl]-2-(2,6-diketo-1,3-dimethyl-purin-7-yl)acetamide | SMR000064223 | cid_2997571 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15ClN6O3S |
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| Mol. Mass. | 430.868 |
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| SMILES | Cn1c2ncn(CC(=O)Nc3nc(cs3)-c3ccccc3Cl)c2c(=O)n(C)c1=O |
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| Structure | 
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