| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM57749 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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| EC50 | 5530±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM57749 |
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| n/a |
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| Name | BDBM57749 |
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| Synonyms: | 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(5-nitro-2-furanyl)-3-oxopropanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(5-nitrofuran-2-yl)-3-oxidanylidene-propanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(5-nitrofuran-2-yl)-3-oxopropanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-keto-3-(5-nitro-2-furyl)propionitrile | MLS000418549 | SMR000265016 | cid_5668947 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H8N4O4 |
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| Mol. Mass. | 296.2377 |
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| SMILES | [O-][N+](=O)c1ccc(o1)C(=O)[C-](C#N)c1[nH]c2ccccc2[nH+]1 |
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| Structure | 
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