Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM83618 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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EC50 | 7910±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM83618 |
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n/a |
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Name | BDBM83618 |
Synonyms: | 4-methyl-N-(1-methylpropylideneamino)-3-nitro-benzenesulfonamide | MLS000775595 | N-(butan-2-ylideneamino)-4-methyl-3-nitro-benzenesulfonamide | N-(butan-2-ylideneamino)-4-methyl-3-nitrobenzenesulfonamide | SMR000370481 | cid_3910353 |
Type | Small organic molecule |
Emp. Form. | C11H15N3O4S |
Mol. Mass. | 285.32 |
SMILES | CC[C+](C)[N-]NS(=O)(=O)c1ccc(C)c(c1)[N+]([O-])=O |
Structure |
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