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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Caspase-9 | ||
| Ligand | BDBM51771 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose response confirmation of uHTS hits for Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay | ||
| IC50 | 145±n/a nM | ||
| Citation |  PubChem, PC Dose response confirmation of uHTS hits for Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay PubChem Bioassay(2011)[AID] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Caspase-9 | |||
| Name: | Caspase-9 | ||
| Synonyms: | Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c | Apoptotic protease-activating factor 3 | CASP-9 | CASP9 | CASP9_HUMAN | Caspase 9 | ICE-like apoptotic protease 6 | MCH6 | caspase-9 isoform alpha preproprotein | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 46277.29 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 416 | ||
| Sequence: |
| ||
| BDBM51771 | |||
| n/a | |||
| Name | BDBM51771 | ||
| Synonyms: | 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione | 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione | 1,6-dimethyl-3-(2-pyridyl)pyrimido[5,4-e][1,2,4]triazine-5,7-quinone | 1,6-dimethyl-3-pyridin-2-yl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione | 1,6-dimethyl-3-pyridin-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione | MLS000684008 | SMR000291658 | cid_906542 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C12H10N6O2 | ||
| Mol. Mass. | 270.2468 | ||
| SMILES | Cn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccn1 | ||
| Structure | 
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