| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-9 |
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| Ligand | BDBM61198 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS hits for Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay |
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| IC50 | 2630±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS hits for Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-9 |
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| Name: | Caspase-9 |
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| Synonyms: | Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c | Apoptotic protease-activating factor 3 | CASP-9 | CASP9 | CASP9_HUMAN | Caspase 9 | ICE-like apoptotic protease 6 | MCH6 | caspase-9 isoform alpha preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 46277.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 416 |
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| Sequence: | MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
LRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTR
TGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQ
ASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVAS
TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
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| BDBM61198 |
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| n/a |
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| Name | BDBM61198 |
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| Synonyms: | 2-methoxybenzaldehyde [2,6-bis(dimethylamino)pyrimidin-4-yl]hydrazone | 6-N-[(2-methoxyphenyl)methylideneamino]-2-N,2-N,4-N,4-N-tetramethylpyrimidine-2,4,6-triamine | MLS000720211 | N6-[(2-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethyl-pyrimidine-2,4,6-triamine | N6-[(2-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethylpyrimidine-2,4,6-triamine | SMR000304740 | [2-(dimethylamino)-6-(N'-o-anisylidenehydrazino)pyrimidin-4-yl]-dimethyl-amine | cid_4035805 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H22N6O |
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| Mol. Mass. | 314.3855 |
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| SMILES | COc1ccccc1CN=Nc1cc(nc(n1)N(C)C)N(C)C |w:10.11| |
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| Structure | 
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