| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-9 |
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| Ligand | BDBM71467 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS hits for Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay |
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| IC50 | 3190±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS hits for Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-9 |
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| Name: | Caspase-9 |
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| Synonyms: | Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c | Apoptotic protease-activating factor 3 | CASP-9 | CASP9 | CASP9_HUMAN | Caspase 9 | ICE-like apoptotic protease 6 | MCH6 | caspase-9 isoform alpha preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 46277.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 416 |
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| Sequence: | MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
LRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTR
TGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQ
ASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVAS
TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
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| BDBM71467 |
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| n/a |
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| Name | BDBM71467 |
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| Synonyms: | 5-Methyl-2H-pyrazole-3-carboxylic acid (5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-ylmethylene)-hydrazide | 5-methyl-N'-[(Z)-(3-methyl-5-oxidanylidene-1-phenyl-pyrazol-4-ylidene)methyl]-1H-pyrazole-3-carbohydrazide | 5-methyl-N'-[(Z)-(3-methyl-5-oxo-1-phenyl-4-pyrazolylidene)methyl]-1H-pyrazole-3-carbohydrazide | 5-methyl-N'-[(Z)-(3-methyl-5-oxo-1-phenylpyrazol-4-ylidene)methyl]-1H-pyrazole-3-carbohydrazide | MLS001219517 | N'-[(Z)-(5-keto-3-methyl-1-phenyl-2-pyrazolin-4-ylidene)methyl]-5-methyl-1H-pyrazole-3-carbohydrazide | SMR000611152 | cid_5765297 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N6O2 |
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| Mol. Mass. | 324.3372 |
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| SMILES | Cc1cc([nH]n1)C(=O)NN=Cc1c(C)[nH]n(-c2ccccc2)c1=O |w:9.9| |
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| Structure | 
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