| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptotic protease-activating factor 1 |
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| Ligand | BDBM83911 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response validation of Activators of Apaf-1 using a Fluorescent Interference Counterscreen assay |
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| EC50 | >100000±0 nM |
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| Citation |  PubChem, PC Dose Response validation of Activators of Apaf-1 using a Fluorescent Interference Counterscreen assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Apoptotic protease-activating factor 1 |
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| Name: | Apoptotic protease-activating factor 1 |
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| Synonyms: | APAF1 | APAF_HUMAN | Apoptotic peptidase activating factor 1 | KIAA0413 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 141834.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14727 |
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| Residue: | 1248 |
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| Sequence: | MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS
INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
STIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLT
EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
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| BDBM83911 |
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| n/a |
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| Name | BDBM83911 |
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| Synonyms: | MLS000590613 | N-(9,10-Dioxo-9,10-dihydro-anthracen-2-yl)-3,4-dimethoxy-benzamide | N-(9,10-diketo-2-anthryl)-3,4-dimethoxy-benzamide | N-(9,10-dioxo-2-anthracenyl)-3,4-dimethoxybenzamide | N-(9,10-dioxoanthracen-2-yl)-3,4-dimethoxybenzamide | N-[9,10-bis(oxidanylidene)anthracen-2-yl]-3,4-dimethoxy-benzamide | SMR000217561 | cid_5185720 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H17NO5 |
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| Mol. Mass. | 387.3848 |
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| SMILES | COc1ccc(cc1OC)C(=O)Nc1ccc2C(=O)c3ccccc3C(=O)c2c1 |
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| Structure | 
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