| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
|---|
| Ligand | BDBM83668 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of small molecule activators of the MazEF TA System via a fluorescence-based single-stranded RNase assay |
|---|
| EC50 | 3350±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of small molecule activators of the MazEF TA System via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Endoribonuclease toxin MazF |
|---|
| Name: | Endoribonuclease toxin MazF |
|---|
| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 12100.43 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130689 |
|---|
| Residue: | 111 |
|---|
| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
|---|
| BDBM83668 |
|---|
| n/a |
|---|
| Name | BDBM83668 |
|---|
| Synonyms: | MLS001124551 | N-(2-furanylmethyl)-4-[[(1,3,3-trimethyl-2-oxo-5-indolyl)sulfonylamino]methyl]benzamide | N-(2-furfuryl)-4-[[(2-keto-1,3,3-trimethyl-indolin-5-yl)sulfonylamino]methyl]benzamide | N-(furan-2-ylmethyl)-4-[[(1,3,3-trimethyl-2-oxidanylidene-indol-5-yl)sulfonylamino]methyl]benzamide | N-(furan-2-ylmethyl)-4-[[(1,3,3-trimethyl-2-oxoindol-5-yl)sulfonylamino]methyl]benzamide | SMR000628631 | cid_20903316 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H25N3O5S |
|---|
| Mol. Mass. | 467.537 |
|---|
| SMILES | CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)NCc1ccc(cc1)C(=O)NCc1ccco1 |
|---|
| Structure | 
|
|---|
Search and Browse
