| Reaction Details |
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 | Report a problem with these data |
| Target | Multidrug efflux pump |
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| Ligand | BDBM65186 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 |
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| EC50 | 312±n/a nM |
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| Citation |  PubChem, PC Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Multidrug efflux pump |
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| Name: | Multidrug efflux pump |
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| Synonyms: | Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cds |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 62915.82 |
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| Organism: | Candida albicans |
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| Description: | Q09GR2 |
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| Residue: | 564 |
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| Sequence: | MHYRFLRDSFVGRVTYHLSKHKYFAHPEEAKDYIVPEKYLADYKPTLADDTSINFEKEEI
DNQGEPNSSQSSSSNNTIVDNNNNNDNDVDGDKIVVTWDGDDDPENPQNWPTLQKAFFIF
QISFLTTSVYMGSAVYTPGIEELMHDFGIGRVVATLPLTLFVIGYGVGPLVFSPMSENAI
FGRTSIYIITLFLFVILQIPTALVNNIAGLCILRFLGGFFASPCLATGGASVADVVKFWN
LPVGLAAWSLGAVCGPSFGPFFGSILTVKASWRWTFWFMCIISGFSFVMLCFTLPETFGK
TLLYRKAKRLRAITGNDRITSEGEIENSKMTSHELIIDTLWRPLEITVMEPVVLLINIYI
AMVYSILYLFFEVFPIYFVGVKHFTLVELGTTYMSIVIGIVIAAFIYIPVIRQKFTKPIL
RQEQVFPEVFIPIAIVGGILLTSGLFIFGWSANRTTHWVGPLFGAATTASGAFLIFQTLF
NFMGASFKPHYIASVFASNDLFRSVIASVFPLFGAPLFDNLATPEYPVAWGSSVLGFITL
VMIAIPVLFYLNGPKLRARSKYAN
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| BDBM65186 |
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| n/a |
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| Name | BDBM65186 |
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| Synonyms: | Dodecyl-dimethyl-prop-2-ynyl-ammonium | MLS000590476 | SMR000217471 | cid_12005722 | dodecyl-dimethyl-prop-2-ynyl-azanium;bromide | dodecyl-dimethyl-prop-2-ynylammonium;bromide | dodecyl-dimethyl-prop-2-ynylazanium;bromide | lauryl-dimethyl-propargyl-ammonium;bromide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H34N |
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| Mol. Mass. | 252.458 |
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| SMILES | CCCCCCCCCCCC[N+](C)(C)CC#C |
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| Structure | 
|
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