| Reaction Details |
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 | Report a problem with these data |
| Target | Multidrug efflux pump |
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| Ligand | BDBM84126 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 |
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| EC50 | 13700±n/a nM |
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| Citation |  PubChem, PC Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Multidrug efflux pump |
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| Name: | Multidrug efflux pump |
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| Synonyms: | Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cds |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 62915.82 |
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| Organism: | Candida albicans |
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| Description: | Q09GR2 |
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| Residue: | 564 |
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| Sequence: | MHYRFLRDSFVGRVTYHLSKHKYFAHPEEAKDYIVPEKYLADYKPTLADDTSINFEKEEI
DNQGEPNSSQSSSSNNTIVDNNNNNDNDVDGDKIVVTWDGDDDPENPQNWPTLQKAFFIF
QISFLTTSVYMGSAVYTPGIEELMHDFGIGRVVATLPLTLFVIGYGVGPLVFSPMSENAI
FGRTSIYIITLFLFVILQIPTALVNNIAGLCILRFLGGFFASPCLATGGASVADVVKFWN
LPVGLAAWSLGAVCGPSFGPFFGSILTVKASWRWTFWFMCIISGFSFVMLCFTLPETFGK
TLLYRKAKRLRAITGNDRITSEGEIENSKMTSHELIIDTLWRPLEITVMEPVVLLINIYI
AMVYSILYLFFEVFPIYFVGVKHFTLVELGTTYMSIVIGIVIAAFIYIPVIRQKFTKPIL
RQEQVFPEVFIPIAIVGGILLTSGLFIFGWSANRTTHWVGPLFGAATTASGAFLIFQTLF
NFMGASFKPHYIASVFASNDLFRSVIASVFPLFGAPLFDNLATPEYPVAWGSSVLGFITL
VMIAIPVLFYLNGPKLRARSKYAN
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| BDBM84126 |
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| n/a |
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| Name | BDBM84126 |
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| Synonyms: | 4-[2-[4-[2-(3,5-dimethoxyphenyl)-5-methoxy-1-benzothiophen-3-yl]phenoxy]ethyl]morpholine | 4-[2-[4-[2-(3,5-dimethoxyphenyl)-5-methoxy-benzothiophen-3-yl]phenoxy]ethyl]morpholine | MLS002603244 | SMR001522219 | cid_44601953 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31NO5S |
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| Mol. Mass. | 505.625 |
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| SMILES | COc1ccc2sc(c(-c3ccc(OCCN4CCOCC4)cc3)c2c1)-c1cc(OC)cc(OC)c1 |
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| Structure | 
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