| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50000082 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_226551 |
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| Ki | 2.1±n/a nM |
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| Citation |  de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the sigma receptor. J Med Chem35:38-47 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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|
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| BDBM50000082 |
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| n/a |
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| Name | BDBM50000082 |
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| Synonyms: | CHEMBL142353 | Methyl-(2-naphthalen-2-yl-ethyl)-(2-pyrrolidin-1-yl-ethyl)-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26N2 |
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| Mol. Mass. | 282.4231 |
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| SMILES | CN(CCN1CCCC1)CCc1ccc2ccccc2c1 |
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| Structure | 
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