| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50000718 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155155 |
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| Ki | 945±n/a nM |
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| Citation |  Guinn, DE; Summers, JB; Heyman, HR; Conway, RG; Rhein, DA; Albert, DH; Magoc, T; Carter, GW Synthesis and structure-activity relationships of a series of novel benzopyran-containing platelet activating factor antagonists. J Med Chem35:2055-61 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50000718 |
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| n/a |
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| Name | BDBM50000718 |
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| Synonyms: | 2-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-methoxy-10,10-dimethyl-1,2,4,10-tetrahydro-9-oxa-3-aza-phenanthren-3-yl}-acetamide | CHEMBL65144 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H35FN2O3 |
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| Mol. Mass. | 466.5875 |
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| SMILES | COc1cc(cc2OC(C)(C)C3=C(CN(CC(N)=O)CC3)c12)C(C)CCCc1ccc(F)cc1 |t:11| |
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| Structure | 
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