| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
|---|
| Ligand | BDBM50000712 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_155155 |
|---|
| Ki | 3250±n/a nM |
|---|
| Citation |  Guinn, DE; Summers, JB; Heyman, HR; Conway, RG; Rhein, DA; Albert, DH; Magoc, T; Carter, GW Synthesis and structure-activity relationships of a series of novel benzopyran-containing platelet activating factor antagonists. J Med Chem35:2055-61 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Platelet-activating factor receptor |
|---|
| Name: | Platelet-activating factor receptor |
|---|
| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 39005.63 |
|---|
| Organism: | Cavia porcellus |
|---|
| Description: | n/a |
|---|
| Residue: | 342 |
|---|
| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
|
|
|
|---|
| BDBM50000712 |
|---|
| n/a |
|---|
| Name | BDBM50000712 |
|---|
| Synonyms: | 7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-10,10-dimethyl-3-prop-2-ynyl-2,3,4,10-tetrahydro-1H-9-oxa-3-aza-phenanthren-5-ol | CHEMBL303312 | TCMDC-124277 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H32FNO2 |
|---|
| Mol. Mass. | 433.5576 |
|---|
| SMILES | CC(CCCc1ccc(F)cc1)c1cc(O)c2C3=C(CCN(CC#C)C3)C(C)(C)Oc2c1 |t:18| |
|---|
| Structure | 
|
|---|
Search and Browse
