| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50000701 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155155 |
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| Ki | 157±n/a nM |
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| Citation |  Guinn, DE; Summers, JB; Heyman, HR; Conway, RG; Rhein, DA; Albert, DH; Magoc, T; Carter, GW Synthesis and structure-activity relationships of a series of novel benzopyran-containing platelet activating factor antagonists. J Med Chem35:2055-61 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50000701 |
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| n/a |
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| Name | BDBM50000701 |
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| Synonyms: | 2-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-10,10-dimethyl-3-methylcarbamoylmethyl-2,3,4,10-tetrahydro-1H-9-oxa-3-aza-phenanthren-5-yloxy}-N,N-dimethyl-acetamide | CHEMBL264497 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H42FN3O4 |
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| Mol. Mass. | 551.692 |
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| SMILES | CNC(=O)CN1CCC2=C(C1)c1c(OCC(=O)N(C)C)cc(cc1OC2(C)C)C(C)CCCc1ccc(F)cc1 |c:8| |
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| Structure | 
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