| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50116368 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1669078 (CHEMBL4018966) |
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| Ki | 3.2±n/a nM |
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| Citation |  Xia, L; Burger, WAC; van Veldhoven, JPD; Kuiper, BJ; van Duijl, TT; Lenselink, EB; Paasman, E; Heitman, LH; IJzerman, AP Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A J Med Chem60:7555-7568 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50116368 |
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| n/a |
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| Name | BDBM50116368 |
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| Synonyms: | 1-Benzyl-7-methoxy-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione | CHEMBL113634 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O3 |
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| Mol. Mass. | 364.3978 |
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| SMILES | CCCn1c(=O)n(Cc2ccccc2)c2nc3cc(OC)ccn3c2c1=O |
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| Structure | 
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