| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM25762 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_37833 |
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| IC50 | 5000±n/a nM |
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| Citation |  Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Synthesis, cardiac electrophysiology, and beta-blocking activity of novel arylpiperazines with potential as class II/III antiarrhythmic agents. J Med Chem35:743-50 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2_CANLF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46593.67 |
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| Organism: | Canis familiaris |
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| Description: | ChEMBL_56504 |
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| Residue: | 415 |
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| Sequence: | MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIAR
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRF
HAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNS
RSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
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|
|
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| BDBM25762 |
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| n/a |
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| Name | BDBM25762 |
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| Synonyms: | CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide | SOTALOL HYDROCHLORIDE | Sotalol | Sotalol,(+) | Sotalol,(-) | cid_66245 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H20N2O3S |
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| Mol. Mass. | 272.364 |
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| SMILES | CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 |
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| Structure | 
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