Reaction Details |
| Report a problem with these data |
Target | Sigma non-opioid intracellular receptor 1 |
---|
Ligand | BDBM50242669 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_1672046 (CHEMBL4022075) |
---|
Ki | 8.4±n/a nM |
---|
Citation | Sguazzini, E; Schmidt, HR; Iyer, KA; Kruse, AC; Dukat, M Reevaluation of fenpropimorph as a? receptor ligand: Structure-affinity relationship studies at human? Bioorg Med Chem Lett27:2912-2919 (2017) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Sigma non-opioid intracellular receptor 1 |
---|
Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25124.85 |
Organism: | Homo sapiens (Human) |
Description: | Q99720 |
Residue: | 223 |
Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
BDBM50242669 |
---|
n/a |
---|
Name | BDBM50242669 |
Synonyms: | CHEMBL4098546 |
Type | Small organic molecule |
Emp. Form. | C19H31NO |
Mol. Mass. | 289.4555 |
SMILES | CC1CN(CCCc2ccc(cc2)C(C)(C)C)CC(C)O1 |
Structure |
|