| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2, major isoenzyme |
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| Ligand | BDBM50004505 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_156346 |
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| IC50 | 4500±n/a nM |
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| Citation |  Bennion, C; Connolly, S; Gensmantel, NP; Hallam, C; Jackson, CG; Primrose, WU; Roberts, GC; Robinson, DH; Slaich, PK Design and synthesis of some substrate analogue inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex. J Med Chem35:2939-51 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2, major isoenzyme |
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| Name: | Phospholipase A2, major isoenzyme |
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| Synonyms: | Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 |
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| Type: | Hydrolase; monomer or homodimer |
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| Mol. Mass.: | 16279.83 |
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| Organism: | Sus scrofa (pig) |
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| Description: | Purchased from Sigma. |
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| Residue: | 146 |
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| Sequence: | MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPV
DELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNC
DRNAAICFSKAPYNKEHKNLDTKKYC
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| BDBM50004505 |
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| n/a |
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| Name | BDBM50004505 |
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| Synonyms: | (S)-O-(2-Hexadecanamidoisohexyl) phosphocholine | CHEMBL101828 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H57N2O5P |
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| Mol. Mass. | 520.7256 |
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| SMILES | CCCCCCCCCCCCCCCC(=O)N[C@H](COP([O-])(=O)OCC[N+](C)(C)C)CC(C)C |
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| Structure | 
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