Ki Summary

Reaction Details

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Target

Kallikrein

Ligand

BDBM50004613

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_92376

135000±n/a nM

Citation

Deshpande, MS; Burton, J Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem35:3094-102 (1992) [PubMed]

More Info.:

Get all data from this article, Assay Method

Kallikrein

Name:

Kallikrein

Synonyms:

Kallikrein 1

Type:

PROTEIN

Mol. Mass.:

72241.51

Organism:

Sus scrofa

Description:

ChEMBL_92376

Residue:

643

Sequence:

MEVIVLFRIISFRQAVYFMCLFAAVSCGCLPQLHKNTFFRGGDVSAMYTPSARHCQMMCT
FHPRCLLFSFLPADSTSVTDKRFGCFLKDSVTGMLPRVLRENAISGHSLKQCGHQIRACH
RDIYKGIDMRGVNFNVSKVKTVEECQERCTNSIHCLFFTYATQAFNNAEYRNNCLLKHSP
GGTPTSIKVLANVESGFSLKPCADSEIGCHMDIFQHLAFSDVDVARVIAPDAFVCRTICT
YHPNCLFFTFYTNAWKIESQRNVCFLKTSHSGTPSFPTPQENAISGYSLLTCKQTLPEPC
HSKIYSEVDFEGEELNVTFVQGANLCQETCTKTIRCQFFTYSLHPEDCRGEKCKCSLRLS
SDGSPTKITHGMRASSGYSLRLCRSGDHSACATKANTRIVGGTDSFLGEWPWQVSLQAKL
RAQNHLCGGSIIGHQWVLTAAHCFDGLSLPDIWRIYGGILNISEITKETPFSQVKEIIIH
QNYKILESGHDIALLKLETPLNYTDFQKPICLPSRDDTNVVYTNCWVTGWGFTEEKGEIQ
NILQKVNIPLVSNEECQKSYRDHKISKQMICAGYKEGGKDACKGESGGPLVCKYNGIWHL
VGTTSWGEGCARREQPGVYTKVIEYMDWILEKTQDDDGQSWMK

BDBM50004613

n/a

Name

BDBM50004613

Synonyms:

1-(2-Acetylamino-3-hydroxy-propionyl)-pyrrolidine-2-carboxylic acid (1-{1-[1-(1-carbamoyl-2-methyl-propylcarbamoyl)-2-hydroxy-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide | CHEMBL322058

Type

Small organic molecule

Emp. Form.

C33H52N10O9

Mol. Mass.

732.8276

SMILES

CC(C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(C)=O)C(N)=O

Structure