| Reaction Details |
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 | Report a problem with these data |
| Target | Advanced glycosylation end product-specific receptor |
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| Ligand | BDBM50249578 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1680052 (CHEMBL4030329) |
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| IC50 | 1750±n/a nM |
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| Citation |  Bongarzone, S; Savickas, V; Luzi, F; Gee, AD Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective. J Med Chem60:7213-7232 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Advanced glycosylation end product-specific receptor |
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| Name: | Advanced glycosylation end product-specific receptor |
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| Synonyms: | AGER | RAGE | RAGE_HUMAN | Receptor for advanced glycosylation end products |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42800.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1339877 |
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| Residue: | 404 |
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| Sequence: | MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI
PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH
PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL
VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS
CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV
ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
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| BDBM50249578 |
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| n/a |
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| Name | BDBM50249578 |
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| Synonyms: | CHEMBL4095634 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H39N3O4 |
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| Mol. Mass. | 505.6484 |
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| SMILES | CCCCOc1cc(ccc1NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)OCCN(CC)CC |r| |
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| Structure | 
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