| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50006711 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29291 |
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| Ki | 1700±n/a nM |
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| Citation |  Shimada, J; Suzuki, F; Nonaka, H; Ishii, A; Ichikawa, S (E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists. J Med Chem35:2342-5 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36501.39 |
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| Organism: | GUINEA PIG |
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| Description: | ADENOSINE A1 ADORA1 GUINEA PIG::P47745 |
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| Residue: | 326 |
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| Sequence: | MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPEPPIDEDLPEEKVDD
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| BDBM50006711 |
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| n/a |
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| Name | BDBM50006711 |
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| Synonyms: | 8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | CHEMBL27496 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N4O4 |
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| Mol. Mass. | 398.4555 |
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| SMILES | CCCn1c2nc(C=Cc3ccc(OC)c(OC)c3)[nH]c2c(=O)n(CCC)c1=O |w:8.8| |
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| Structure | 
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