| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50006992 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201262 (CHEMBL804880) |
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| IC50 | 10±n/a nM |
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| Citation |  Wilson, AA; Dannals, RF; Ravert, HT; Sonders, MS; Weber, E; Wagner, HN Radiosynthesis of sigma receptor ligands for positron emission tomography: 11C- and 18F-labeled guanidines. J Med Chem34:1867-70 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50006992 |
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| n/a |
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| Name | BDBM50006992 |
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| Synonyms: | CHEMBL292668 | N-Adamantan-1-yl-N'-(4-methoxy-phenyl)-guanidine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H25N3O |
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| Mol. Mass. | 299.4106 |
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| SMILES | COc1ccc(NC(N)=NC23CC4CC(CC(C4)C2)C3)cc1 |w:9.9,TLB:17:16:19:12.11.13,17:12:19:16.18.15,THB:15:16:11:14.19.13,15:14:11:16.18.17| |
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| Structure | 
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