| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Polyamine deacetylase HDAC10 |
|---|
| Ligand | BDBM50246866 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1686580 (CHEMBL4037059) |
|---|
| IC50 | >20000±n/a nM |
|---|
| Citation |  Bourguet, E; Ozdarska, K; Moroy, G; Jeanblanc, J; Naassila, M Class I HDAC Inhibitors: Potential New Epigenetic Therapeutics for Alcohol Use Disorder (AUD). J Med Chem61:1745-1766 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Polyamine deacetylase HDAC10 |
|---|
| Name: | Polyamine deacetylase HDAC10 |
|---|
| Synonyms: | HD10 | HDA10_HUMAN | HDAC10 | Histone deacetylase | Histone deacetylase 10 | Human HDAC10 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 71431.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q969S8 |
|---|
| Residue: | 669 |
|---|
| Sequence: | MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEEL
GLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTG
AVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQ
YLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVA
AFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAV
LEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQ
DVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPD
ITLVLPPDVIQQEASALREETEAWARPHESLAREEALTALGKLLYLLDGMLDGQVNSGIA
ATPASAAAATLDVAVRRGLSHGAQRLLCVALGQLDRPPDLAHDGRSLWLNIRGKEAAALS
MFHVSTPLPVMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAAMLRGL
AGGRVLALLEENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM
LQCHPHLVA
|
|
|
|---|
| BDBM50246866 |
|---|
| n/a |
|---|
| Name | BDBM50246866 |
|---|
| Synonyms: | CHEMBL4078458 | US11505523, Compound 22d |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H19NO3 |
|---|
| Mol. Mass. | 345.3912 |
|---|
| SMILES | COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
