| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50008076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_138791 |
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| IC50 | 10200±n/a nM |
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| Citation |  Shapiro, G; Floersheim, P; Boelsterli, J; Amstutz, R; Bolliger, G; Gammenthaler, H; Gmelin, G; Supavilai, P; Walkinshaw, M Muscarinic activity of the thiolactone, lactam, lactol, and thiolactol analogues of pilocarpine and a hypothetical model for the binding of agonists to the m1 receptor. J Med Chem35:15-27 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50008076 |
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| n/a |
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| Name | BDBM50008076 |
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| Synonyms: | 3-Ethyl-1-methyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-pyrrolidin-2-one | CHEMBL90532 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H19N3O |
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| Mol. Mass. | 221.2988 |
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| SMILES | CC[C@H]1[C@@H](Cc2cncn2C)CN(C)C1=O |
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| Structure | 
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