| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50256756 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1688177 |
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| Ki | 50±n/a nM |
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| Citation |  Adamska-Bart?omiejczyk, A; De Marco, R; Gentilucci, L; Kluczyk, A; Janecka, A Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold. Bioorg Med Chem25:2399-2405 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50256756 |
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| n/a |
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| Name | BDBM50256756 |
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| Synonyms: | CHEMBL4074931 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H45N7O7 |
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| Mol. Mass. | 663.7638 |
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| SMILES | N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@@H]2CCCCN2C(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O |r| |
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| Structure | 
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