| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM50258176 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1690270 |
|---|
| IC50 | 19±n/a nM |
|---|
| Citation |  Fonseca, A; Reis, J; Silva, T; Matos, MJ; Bagetta, D; Ortuso, F; Alcaro, S; Uriarte, E; Borges, F Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis? J Med Chem60:7206-7212 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 58768.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P27338 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
|
|
|
|---|
| BDBM50258176 |
|---|
| n/a |
|---|
| Name | BDBM50258176 |
|---|
| Synonyms: | CHEMBL4089520 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H12ClNO4 |
|---|
| Mol. Mass. | 329.734 |
|---|
| SMILES | COc1ccc2oc(=O)c(cc2c1)C(=O)Nc1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
