| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transmembrane domain-containing protein TMIGD3 |
|---|
| Ligand | BDBM50259313 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1691284 (CHEMBL4041933) |
|---|
| Ki | 312±n/a nM |
|---|
| Citation |  Poli, D; Falsini, M; Varano, F; Betti, M; Varani, K; Vincenzi, F; Pugliese, AM; Pedata, F; Dal Ben, D; Thomas, A; Palchetti, I; Bettazzi, F; Catarzi, D; Colotta, V Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A Eur J Med Chem125:611-628 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transmembrane domain-containing protein TMIGD3 |
|---|
| Name: | Transmembrane domain-containing protein TMIGD3 |
|---|
| Synonyms: | TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 30335.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_114868 |
|---|
| Residue: | 266 |
|---|
| Sequence: | MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMW
LFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAF
SPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLA
NDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQR
NRRVGNTLKPFSRVLTPKEMAPTEQM
|
|
|
|---|
| BDBM50259313 |
|---|
| n/a |
|---|
| Name | BDBM50259313 |
|---|
| Synonyms: | CHEMBL4099880 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H20N4O2 |
|---|
| Mol. Mass. | 420.4626 |
|---|
| SMILES | COc1ccc(cc1)-c1cn2cc(nc(NC(=O)c3ccccc3)c2n1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
