| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK4 |
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| Ligand | BDBM50259412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1691313 |
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| IC50 | 410±n/a nM |
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| Citation |  Bendjeddou, LZ; Loaëc, N; Villiers, B; Prina, E; Späth, GF; Galons, H; Meijer, L; Oumata, N Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor. Eur J Med Chem125:696-709 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK4 |
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| Name: | Dual specificity protein kinase CLK4 |
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| Synonyms: | CDC-like kinase 4 | CLK4_MOUSE | Clk4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57374.39 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1502248 |
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| Residue: | 481 |
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| Sequence: | MRHSKRTHCPDWDSRESWGHESYSGSHKRKRRSHSSTQENRHCKPHHQFKDSDCHYLEAR
CLNERDYRDRRYIDEYRNDYCEGYVPRHYHRDVESTYRIHCSKSSVRSRRSSPKRKRNRP
CASHQSHSKSHRRKRSRSIEDDEEGHLICQSGDVLRARYEIVDTLGEGAFGKVVECIDHG
MDGLHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFE
LLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYV
VKYNSKMKRDERTLKNTDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDV
WSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHMIQKTRKRKYFHHNQLDWDEH
SSAGRYVRRRCKPLKEFMLCHDEEHEKLFDLVRRMLEYDPARRITLDEALQHPFFDLLKR
K
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| BDBM50259412 |
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| n/a |
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| Name | BDBM50259412 |
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| Synonyms: | CHEMBL4080844 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19F3N4O |
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| Mol. Mass. | 376.3756 |
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| SMILES | CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 |r| |
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| Structure | 
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