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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A | ||
| Ligand | BDBM50259924 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_1691999 | ||
| IC50 | 14500±n/a nM | ||
| Citation |  Hill, MD; Fang, H; Digavalli, SV; Healy, FL; Gallagher, L; Post-Munson, D; Chen, P; Natale, J; Benitex, Y; Morgan, D; Lodge, N; Bristow, L; Macor, JE; Olson, RE Development of spiroguanidine-derived?7 neuronal nicotinic receptor partial agonists. Bioorg Med Chem Lett27:578-581 (2017) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 3A | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 55283.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46098 | ||
| Residue: | 478 | ||
| Sequence: |
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| BDBM50259924 | |||
| n/a | |||
| Name | BDBM50259924 | ||
| Synonyms: | CHEMBL4096397 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H20N6 | ||
| Mol. Mass. | 308.3809 | ||
| SMILES | C1N=C(Nc2ncnc3ccccc23)NC11CN2CCC1CC2 |t:1,THB:14:15:18.19:21.22,(17.8,-17.06,;18.95,-16.03,;18.32,-14.62,;19.1,-13.29,;20.64,-13.29,;21.41,-11.95,;22.95,-11.95,;23.73,-13.29,;22.95,-14.63,;23.71,-15.96,;22.95,-17.28,;21.4,-17.28,;20.64,-15.95,;21.41,-14.62,;16.79,-14.78,;16.47,-16.29,;16.26,-17.68,;14.34,-16.87,;12.93,-17.8,;13.28,-16.4,;14.98,-15.65,;14.92,-14.01,;14.33,-15.4,)| | ||
| Structure | 
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