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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A | ||
| Ligand | BDBM50259938 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_1691999 | ||
| IC50 | 26±n/a nM | ||
| Citation |  Hill, MD; Fang, H; Digavalli, SV; Healy, FL; Gallagher, L; Post-Munson, D; Chen, P; Natale, J; Benitex, Y; Morgan, D; Lodge, N; Bristow, L; Macor, JE; Olson, RE Development of spiroguanidine-derived?7 neuronal nicotinic receptor partial agonists. Bioorg Med Chem Lett27:578-581 (2017) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 3A | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 55283.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46098 | ||
| Residue: | 478 | ||
| Sequence: |
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| BDBM50259938 | |||
| n/a | |||
| Name | BDBM50259938 | ||
| Synonyms: | CHEMBL4104136 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H19N5O | ||
| Mol. Mass. | 297.355 | ||
| SMILES | C1N=C(Nc2nc3ccccc3o2)NC11CN2CCC1CC2 |t:1,THB:13:14:17.18:20.21,(44.73,-15.9,;45.88,-14.88,;45.25,-13.47,;46.02,-12.13,;47.57,-12.13,;48.47,-13.37,;49.94,-12.9,;51.27,-13.67,;52.61,-12.9,;52.6,-11.35,;51.27,-10.59,;49.94,-11.35,;48.48,-10.88,;43.72,-13.63,;43.4,-15.13,;43.19,-16.52,;41.27,-15.71,;39.87,-16.64,;40.21,-15.24,;41.91,-14.49,;41.85,-12.85,;41.26,-14.24,)| | ||
| Structure | 
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