Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSignal transduction protein TRAP
LigandBDBM50260002
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1692279 (CHEMBL4042928)
EC50 6320±n/a nM
Citation Vermote, ABrackman, GRisseeuw, MDCappoen, DCos, PCoenye, TVan Calenbergh, S Novel Potentiators for Vancomycin in the Treatment of Biofilm-Related MRSA Infections via a Mix and Match Approach. ACS Med Chem Lett8:38-42 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Signal transduction protein TRAP
Name:Signal transduction protein TRAP
Synonyms:Signal transduction protein TRAP | TRAP_STAAM | Target of RNAIII-activating protein | traP
Type:PROTEIN
Mol. Mass.:19547.99
Organism:Staphylococcus aureus (strain Mu50 / ATCC 700699)
Description:ChEMBL_117552
Residue:167
Sequence:
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIG
EFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGF
ADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50260002
n/a
NameBDBM50260002
Synonyms:CHEMBL4096484
TypeSmall organic molecule
Emp. Form.C20H23ClN2O4
Mol. Mass.390.861
SMILESO[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNCc1ccccc1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: