| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50009746 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_123445 |
|---|
| IC50 | 20±n/a nM |
|---|
| Citation |  Harfenist, M; McGee, DP; White, HL A selective, reversible, competitive inhibitor of monoamine oxidase A containing no nitrogen, with negligible potentiation of tyramine-induced blood pressure rise. J Med Chem34:2931-3 (1991) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 59515.21 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 526 |
|---|
| Sequence: | MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHV
KWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLA
YLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNI
NVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKL
SSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPM
GAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADR
QAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKD
VPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
|
|
|
|---|
| BDBM50009746 |
|---|
| n/a |
|---|
| Name | BDBM50009746 |
|---|
| Synonyms: | 2-(10,10-Dioxo-10H-10lambda*6*-phenoxathiin-1-yl)-ethanol | CHEMBL66677 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H12O4S |
|---|
| Mol. Mass. | 276.308 |
|---|
| SMILES | OCCc1cccc2Oc3ccccc3S(=O)(=O)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
