| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
|---|
| Ligand | BDBM50100962 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1695435 |
|---|
| IC50 | 10000±n/a nM |
|---|
| Citation |  Pan, X; Iyer, KA; Liu, H; Sweet, DH; Dukat, M A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). Bioorg Med Chem Lett27:4440-4445 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 1 |
|---|
| Name: | Solute carrier family 22 member 1 |
|---|
| Synonyms: | Adrenergic Alpha | OCT1 | Organic cation transporter 1 | S22A1_HUMAN | SLC22A1 | Solute carrier family 22 member 1 | hOCT1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 61154.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Adrenergic Alpha 0 HUMAN::O15245 |
|---|
| Residue: | 554 |
|---|
| Sequence: | MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
|
|
|
|---|
| BDBM50100962 |
|---|
| n/a |
|---|
| Name | BDBM50100962 |
|---|
| Synonyms: | 1N-amino(immino)methyl-4-methylaniline | CHEMBL43415 | N-(4-methylphenyl)guanidine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H11N3 |
|---|
| Mol. Mass. | 149.193 |
|---|
| SMILES | [#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7] |
|---|
| Structure | 
|
|---|
Search and Browse
