| Reaction Details |
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 | Report a problem with these data |
| Target | Adenylate cyclase type 1 |
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| Ligand | BDBM50010275 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_31291 |
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| Kd | 174±n/a nM |
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| Citation |  Robbins, JD; Laurenza, A; Kosley, RW; O'Malley, GJ; Spahl, B; Seamon, KB (Aminoalkyl)carbamates of forskolin: intermediates for the synthesis of functionalized derivatives of forskolin with different specificities for adenylyl cyclase and the glucose transporter. J Med Chem34:3204-12 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenylate cyclase type 1 |
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| Name: | Adenylate cyclase type 1 |
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| Synonyms: | ADCY1 | ADCY1_BOVIN | Adenylate cyclase type I |
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| Type: | PROTEIN |
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| Mol. Mass.: | 124005.57 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_31291 |
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| Residue: | 1134 |
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| Sequence: | MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQ
AATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ
LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLP
VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYGIFVRILAERA
QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR
HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS
GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV
WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP
SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA
LRTASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERE
RKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT
RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPV
LPVPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGA
GAISGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRIL
FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL
NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIE
MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR
IQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPF
GRAGLQTRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA
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| BDBM50010275 |
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| n/a |
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| Name | BDBM50010275 |
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| Synonyms: | CHEMBL324463 | {2-[3-(4-Hydroxy-phenyl)-propionylamino]-ethyl}-carbamic acid 5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-6-yl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C32H46N2O9 |
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| Mol. Mass. | 602.7156 |
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| SMILES | CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](OC(=O)NCCNC(=O)CCc1ccc(O)cc1)[C@H](O)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C |
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| Structure | 
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