| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium-dependent serotonin transporter |
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| Ligand | BDBM50010589 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_202308 (CHEMBL882267) |
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| Kd | 0.104000±n/a nM |
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| Citation |  Nichols, DE; Brewster, WK; Johnson, MP; Oberlender, R; Riggs, RM Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA). J Med Chem33:703-10 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium-dependent serotonin transporter |
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| Name: | Sodium-dependent serotonin transporter |
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| Synonyms: | 5-HT Transporter | 5-HTT | 5HT transporter | 5HTT | Anandamid membrane transporter, AMT | Anandamide membrane transporter, AMT | Monoamine transporters; Norepinephrine & serotonin | SC6A4_RAT | Slc6a4 | Sodium-dependent serotonin transporter | Sodium-dependent serotonin transporter (SERT) | imipramine receptor |
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| Type: | Multi-pass membrane protein |
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| Mol. Mass.: | 70168.43 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P31652 |
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| Residue: | 630 |
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| Sequence: | METTPLNSQKVLSECKDREDCQENGVLQKGVPTTADRAEPSQISNGYSAVPSTSAGDEAS
HSIPAATTTLVAEIRQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLP
YTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTII
AWALYYLISSLTDRLPWTSCTNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIH
QSKGLQDLGTISWQLTLCIVLIFTVIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGA
TLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQD
ALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPAS
TFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCVLGSLLT
LTSGGAYVVTLLEEYATGPAVLTVALIEAVAVSWFYGITQFCSDVKEMLGFSPGWFWRIC
WVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIVLGYCIGMSSVICIPTYIIYRLIST
PGTLKERIIKSITPETPTEIPCGDIRMNAV
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| BDBM50010589 |
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| n/a |
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| Name | BDBM50010589 |
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| Synonyms: | 6,7-Dihydro-5H-indeno[5,6-d][1,3]dioxol-6-ylamine | CHEMBL162375 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H11NO2 |
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| Mol. Mass. | 177.1998 |
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| SMILES | NC1Cc2cc3OCOc3cc2C1 |
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| Structure | 
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