| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
|---|
| Ligand | BDBM50266936 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1701592 (CHEMBL4052574) |
|---|
| IC50 | 13±n/a nM |
|---|
| Citation |  Lanier, M; Cole, DC; Istratiy, Y; Klein, MG; Schwartz, PA; Tjhen, R; Jennings, A; Hixon, MS Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes. J Med Chem60:5209-5215 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
|---|
| Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
|---|
| Synonyms: | Autotaxin | Autotaxin (mATX) | ENPP2_MOUSE | Ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | Enpp2 | Npps2 | Pdnp2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 98896.47 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | n/a |
|---|
| Residue: | 862 |
|---|
| Sequence: | MARQGCFGSYQVISLFTFAIGVNLCLGFTASRIKRAEWDEGPPTVLSDSPWTNTSGSCKG
RCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCS
EDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKK
GSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDAT
FHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERP
SVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHG
MEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHF
KPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKV
NSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFR
PTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLEELNKRLHTKGSTEERHLLYGR
PAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSP
GFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLV
KKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQP
ADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRK
TSRSYSEILTLKTYLHTYESEI
|
|
|
|---|
| BDBM50266936 |
|---|
| n/a |
|---|
| Name | BDBM50266936 |
|---|
| Synonyms: | CHEMBL4078601 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H24BCl2N3O3S |
|---|
| Mol. Mass. | 492.226 |
|---|
| SMILES | OB(O)c1cccc(CCN2CCN(CC2)c2nc(O)c(Cc3ccc(Cl)c(Cl)c3)s2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
