Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50011684 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_158641 |
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IC50 | 4±n/a nM |
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Citation | Rich, DH; Sun, CQ; Vara Prasad, JV; Pathiasseril, A; Toth, MV; Marshall, GR; Clare, M; Mueller, RA; Houseman, K Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes. J Med Chem34:1222-5 (1991) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50011684 |
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n/a |
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Name | BDBM50011684 |
Synonyms: | CHEMBL3350878 | Cbz-Asn-Phe-HEA(S)-Pro-Ile-Phe-OMe |
Type | Small organic molecule |
Emp. Form. | C43H56N6O9 |
Mol. Mass. | 800.9395 |
SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC |
Structure |
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