| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 2 |
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| Ligand | BDBM17847 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1702324 (CHEMBL4053557) |
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| IC50 | >300000±n/a nM |
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| Citation |  White, KN; Tenney, K; Crews, P The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects. J Nat Prod80:740-755 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 2 |
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| Name: | Methionine aminopeptidase 2 |
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| Synonyms: | Initiation factor 2-associated 67 kDa glycoprotein | MAP 2 | MAP2_HUMAN | METAP2 | MNPEP | MetAP 2 | Methionine aminopeptidase 2 (MetAP2) | Methionine aminopeptidases (HsMetAP2) | P67EIF2 | Peptidase M 2 | p67 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52884.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50579 |
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| Residue: | 478 |
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| Sequence: | MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
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| BDBM17847 |
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| n/a |
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| Name | BDBM17847 |
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| Synonyms: | CHEMBL327579 | pyridine-2-carboxylic acid inhibitor, 1 | tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin-3-yl]carbamate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N4O3S |
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| Mol. Mass. | 320.367 |
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| SMILES | CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1 |
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| Structure | 
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