| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
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| Ligand | BDBM50011943 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_48267 |
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| IC50 | 16±n/a nM |
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| Citation |  Yu, MJ; Thrasher, KJ; McCowan, JR; Mason, NR; Mendelsohn, LG Quinazolinone cholecystokinin-B receptor ligands. J Med Chem34:1505-8 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin/cholecystokinin type B receptor |
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| Name: | Gastrin/cholecystokinin type B receptor |
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| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49196.59 |
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| Organism: | MOUSE |
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| Description: | Cholecystokinin A CCKBR MOUSE::P56481 |
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| Residue: | 453 |
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| Sequence: | MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGL
ISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCY
VQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANT
WRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPR
ARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
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| BDBM50011943 |
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| n/a |
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| Name | BDBM50011943 |
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| Synonyms: | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-dimethylamino-phenyl)-3H-quinazolin-4-one | CHEMBL37096 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H23BrN4O |
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| Mol. Mass. | 487.391 |
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| SMILES | CN(C)c1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O |
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| Structure | 
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