| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50271616 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1711228 (CHEMBL4121277) |
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| EC50 | 240±n/a nM |
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| Citation |  Darwish, KM; Salama, I; Mostafa, S; Gomaa, MS; Khafagy, ES; Helal, MA Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-?/FFAR1 agonists. Bioorg Med Chem Lett28:1595-1602 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50271616 |
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| n/a |
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| Name | BDBM50271616 |
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| Synonyms: | CHEMBL4127920 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H30O2 |
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| Mol. Mass. | 278.4296 |
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| SMILES | CCCCC\C=C\C\C=C\C\C=C\CCCCC(O)=O |
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| Structure | 
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