| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50013943 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_148837 |
|---|
| Ki | 0.130000±n/a nM |
|---|
| Citation |  Lalinde, N; Moliterni, J; Wright, D; Spencer, HK; Ossipov, MH; Spaulding, TC; Rudo, FG Synthesis and pharmacological evaluation of a series of new 3-methyl-1,4-disubstituted-piperidine analgesics. J Med Chem33:2876-82 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44503.11 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
|---|
| Residue: | 398 |
|---|
| Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50013943 |
|---|
| n/a |
|---|
| Name | BDBM50013943 |
|---|
| Synonyms: | CHEMBL327270 | Furan-2-carboxylic acid (2-chloro-phenyl)-(3-methyl-1-phenethyl-piperidin-4-yl)-amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H27ClN2O2 |
|---|
| Mol. Mass. | 422.947 |
|---|
| SMILES | CC1CN(CCc2ccccc2)CCC1N(C(=O)c1ccco1)c1ccccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
