| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucagon-like peptide 1 receptor |
|---|
| Ligand | BDBM50241203 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1714751 (CHEMBL4124800) |
|---|
| EC50 | 0.000400±n/a nM |
|---|
| Citation |  Evers, A; Bossart, M; Pfeiffer-Marek, S; Elvert, R; Schreuder, H; Kurz, M; Stengelin, S; Lorenz, M; Herling, A; Konkar, A; Lukasczyk, U; Pfenninger, A; Lorenz, K; Haack, T; Kadereit, D; Wagner, M Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations. J Med Chem61:5580-5593 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucagon-like peptide 1 receptor |
|---|
| Name: | Glucagon-like peptide 1 receptor |
|---|
| Synonyms: | GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 53035.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43220 |
|---|
| Residue: | 463 |
|---|
| Sequence: | MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL
FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW
RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH
LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN
YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN
SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL
GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW
RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
|
|
|
|---|
| BDBM50241203 |
|---|
| n/a |
|---|
| Name | BDBM50241203 |
|---|
| Synonyms: | CHEMBL414357 | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPPS-NH2 | exenatide | exendin-4 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C184H282N50O60S |
|---|
| Mol. Mass. | 4186.572 |
|---|
| SMILES | n/a |
|---|
| Structure | 
|
|---|
Search and Browse
