| Reaction Details |
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 | Report a problem with these data |
| Target | Choline kinase alpha |
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| Ligand | BDBM50275705 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1714831 (CHEMBL4124880) |
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| IC50 | 1630±n/a nM |
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| Citation |  Schiafino-Ortega, S; Baglioni, E; Pérez-Moreno, G; Marco, PR; Marco, C; González-Pacanowska, D; Ruiz-Pérez, LM; Carrasco-Jiménez, MP; López-Cara, LC 1,2-Diphenoxiethane salts as potent antiplasmodial agents. Bioorg Med Chem Lett28:2485-2489 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Choline kinase alpha |
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| Name: | Choline kinase alpha |
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| Synonyms: | CHK | CHKA | CHKA_HUMAN | CKI | Choline kinase alpha |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52248.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1290064 |
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| Residue: | 457 |
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| Sequence: | MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP
PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL
SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE
SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM
PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV
VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP
FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW
GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
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| BDBM50275705 |
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| n/a |
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| Name | BDBM50275705 |
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| Synonyms: | CHEMBL4129845 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H38Br2Cl2N4O2 |
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| Mol. Mass. | 837.469 |
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| SMILES | [Br-].[Br-].CN(c1ccc(Cl)cc1)c1cc[n+](Cc2ccc(OCCOc3ccc(C[n+]4ccc(cc4)N(C)c4ccc(Cl)cc4)cc3)cc2)cc1 |
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| Structure | 
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